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Avoid use of nsaids, including feldene, in pregnant women starting at 30 weeks of gestation third trimester see use in specific populations .

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Patients should be advised of the signs and symptoms and monitored closely for skin reactionsThe highest risk for occurrence of SJS or TEN is within the first weeks of treatment.

AnticoagulantsNSAIDsincluding piroxicammay enhance the effects of anticoagulantssuch as warfarinTherefore the use of piroxicam with concomitant anticoagulant such as warfarin should be avoidedsee section 4.3

In controlled clinical trialsthe effectiveness of FELDENE has been established for both acute exacerbations and long term management of rheumatoid arthritis and osteoarthritis.

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a blood thinner such as warfarin coumadin ; cyclosporine gengraf, neoral, sandimmune ; digoxin digitalis, lanoxin ; lithium eskalith, lithobid ; methotrexate rheumatrex, trexall ; a diuretic water pills such as furosemide lasix ; steroids prednisone and others ; aspirin or other nsaids non-steroidal anti-inflammatory drugs such as diclofenac cataflam, voltaren , flurbiprofen ansaid , indomethacin indocin , ketoprofen orudis , ketorolac toradol , mefenamic acid ponstel , meloxicam mobic , nabumetone relafen , naproxen aleve, naprosyn , piroxicam feldene , and others; or an ace inhibitor such as benazepril lotensin , captopril capoten , fosinopril monopril , enalapril vasotec , lisinopril prinivil, zestril , ramipril altace , and others.

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