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Information about Dapoxetine.
Past studies have revealed high discontinuation rates among men taking dapoxetine for PEeven though trials have shown effectivenessThe current study reported on discontinuation rates and reasons during a 2-year period.
1 Department of UrologySisli Etfal Training and Research HospitalIstanbulTurkey.
To learn more about this studyyou or your doctor may contact the study research staff using the contact information provided by the sponsor.
Expulsion refers to the forcible antegrade propulsion of semen through the urethral meatuswhich is caused by contractions of the periurethral and pelvic floor muscles and concurrent relaxation of the external urethral sphincter and urogenital diaphragmThe sympathetic nervous system controls both emission and bladder neck closureand acts through alpha adrenergic receptorsThe neural signals that lead to ejaculation originate from afferent-sensory stimuli in the glans penis and genitaliaThese stimuli are transmitted by means of the pudendal nerve to higher centers in the brainWitt and Grantmyre 1993
A Study of the Effectiveness and Safety of Dapoxetine in the Treatment of Men With Premature Ejaculation.
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dapoxetine is a rapid acting ssri with a short half-life that was the first approved oral medication for the treatment of premature ejaculation.