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Postmarketing reportsAgranulocytosisaplastic anemiadecreased prothrombinhemolytic anemiaidiopathic thrombocytopenia purpuraincreased INRRef]

There have been rare postmarketing reports describing patients with weaknesshyperreflexiaand incoordination following the use of an SSRI and sumatriptanIf concomitant treatment with sumatriptan and an SSRIe.gfluoxetinefluvoxamineparoxetinesertralinecitalopramescitalopramis clinically warrantedappropriate observation of the patient is advised.

Escitalopram may cause a condition that affects the heart rhythmQT prolongationQT prolongation can rarely cause seriousrarely fatalfast/irregular heartbeat and other symptomssuch as severe dizzinessfaintingthat need medical attention right away.

Taking Lexapro with other drugs that make you sleepy can worsen this effectAsk your doctor before taking a sleeping pillnarcotic medicationmuscle relaxeror medicine for anxietydepressionor seizures.

Serotonin release by platelets plays an important role in hemostasisEpidemiological studies of the case-control and cohort design that have demonstrated an association between use of psychotropic drugs that interfere with serotonin reuptake and the occurrence of upper gastrointestinal bleeding have also shown that concurrent use of an NSAID or aspirin may potentiate the risk of bleedingAltered anticoagulant effectsincluding increased bleedinghave been reported when SSRIs and SNRIs are coadministered with warfarinPatients receiving warfarin therapy should be carefully monitored when Lexapro is initiated or discontinued.

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the potential dose dependency of common adverse reactions defined as an incidence rate of 5 in either the 10 mg or 20 mg lexapro groups was examined on the basis of the combined incidence of adverse reactions in two fixed-dose trials.

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