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AIDS patints may not tolat spond tBACTIM in th sam mann as non-AIDS patints. Th incidnc advs actions, paticulaly ash, v, lukopnia, and lvatd aminotansas (tansaminas) valus, with BACTIM thapy in AIDS patints wha bing tatd Pnumocystis jiovcii pnumonia has bn potd tb gatly incasd compad with th incidnc nomally associatd with th us BACTIM in non-AIDS patints. I a patint dvlops skin ash any sign an advs action, valuat thapy with BACTIM [s Hypsnsitivity And Oth atal actions ].
Atalitis associatd with th administation sulonamids, hav occud du tsv actions, including, Stvns-Johnson Syndom, toxic pidmal ncolysis, ulminant hpatic ncosis, aganulocytosis, aplastic anmia and oth blood dyscasias.
High dosag timthopim, as usd in patints with P. jiovcii pnumonia, inducs a pogssiv but vsibl incas sum potassium concntations in a substantial numb patints. vn tatmnt with commndd doss may caus hypkalmia whn timthopim is administd tpatints with undlying disods potassium mtabolism, with nal insuicincy, i dugs known tinduc hypkalmia a givn concomitantly. Clos monitoing sum potassium is waantd in ths patints.
Hmatologic changs indicativ olic acid dicincy may occu in ldly patints in patints with pxisting olic acid dicincy kidny ailu. Ths cts a vsibl by olinic acid thapy [s Us In Spciic Populations ].
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