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Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and deathResulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformationsPotential neonatal adverse effects include skull hypoplasiaanuriahypotensionrenal failureand deathWhen pregnancy is detecteddiscontinue Diovan as soon as possibleThese adverse outcomes are usually associated with use of these drugs in the second and third trimesters of pregnancyMost epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in the first trimester have not distinguished drugs affecting the renin-angiotensin system from other antihypertensive agentsAppropriate management of maternal hypertension during pregnancy is important to optimize outcomes for both mother and fetus.
In the unusual case that there is no appropriate alternative to therapy with drugs affecting the reninangiotensin system for a particular patientapprise the mother of the potential risk to the fetusPerform serial ultrasound examinations to assess the intra-amniotic environmentIf oligohydramnios is observeddiscontinue Diovanunless it is considered lifesaving for the motherFetal testing may be appropriatebased on the week of pregnancyPatients and physicians should be awarehoweverthat oligohydramnios may not appear until after the fetus has sustained irreversible injuryClosely observe infants with histories of in utero exposure to Diovan for hypotensionoliguriaand hyperkalemiasee Pediatric Use
Talk with your doctor if your symptoms do not improve after 4 weeks of treatment.
Do not use potassium supplements or salt substitutes while you are taking valsartanunless your doctor has told you to.
Keep your tablets in the original container until it is time to take themStore them in a cool dry placeroom temperatureDo not store Diovan or any other medicine in the bathroom or near a sinkDo not leave it in the car or on window sillsHeat and dampness can destroy some medicinesDiovan will keep well if it is cool and dry.
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is there a generic brand that is similar to diovan, as diovan is very expensive.