By stopping your daily dose of keppra xr suddenly, you may suffer from increased seizures.
Information about Keppra.
Although the pattern of adverse reactions in this study seems somewhat different from that seen in patients with partial seizuresthis is likely due to the much smaller number of patients in this study compared to partial seizure studiesThe adverse reaction pattern for patients with primary generalized tonic-clonicPGTCseizures is expected to be essentially the same as for patients with partial seizures.
Pre-marketing data from clinical studies conducted in adults indicate that levetiracetam did not influence the serum concentrations of existing antiepileptic medicinal productsphenytoincarbamazepinevalproic acidphenobarbitallamotriginegabapentin and primidoneand that these antiepileptic medicinal products did not influence the pharmacokinetics of levetiracetam.
Levetiracetam induces seizure protection in a broad range of animal models of partial and primary generalised seizures without having a pro-convulsant effectThe primary metabolite is inactive.
Thereforepatients should be monitored for signs of depression and/or suicidal ideation and behaviours and appropriate treatment should be consideredPatientsand caregivers of patientsshould be advised to seek medical advice should signs of depression and/or suicidal ideation or behaviour emerge.
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the use of keppra xr in pediatric patients 12 years of age and older is supported by study 5, which was conducted using immediate-release keppra.