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Adjuvantpost-surgerytreatment of hormone receptor positive invasive early breast cancerExtended adjuvant treatment of hormone-dependent invasive breast cancer in women who have received prior standard adjuvant tamoxifen therapy for five yearsFirst-line treatment for hormone-dependent advanced breast cancerAdvanced breast cancer after relapse or disease progressionin women with natural or artificially induced postmenopausal endocrine statuswho have previously been treated with anti-oestrogensNeo-adjuvantpre-surgerytreatment of hormone receptor positiveHER-2 negative breast cancer where chemotherapy is not suitable and immediate surgery not indicated.

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