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In the 2 controlled 12-week studiesCOMBIVENT Inhalation Aerosol did not produce any change in the secondary efficacy parameters including symptom scoresphysician global assessments and morning PEFRall of which were monitored throughout the study period.
Stop using albuterol and ipratropium and call your doctor at once if you have a serious side effect such as:
Table 1All Adverse Eventsin percentagesfrom Two Large Double-blindParallel12-Week Studies of Patients with COPD*
Bladder pain bloody or cloudy urine blurred vision burning while urinating burningcrawlingitchingnumbnesspricklingpins and needlesor tingling feelings chest pain congestion diarrhea difficultburningor painful urination dizziness fainting fastslowirregularpoundingor racing heartbeat or pulse frequent urge to urinate general feeling of discomfort or illness hoarseness increased sputum joint pain loss of appetite lower back or side pain muscle aches and pains nausea nervousness noisy breathing pain pain or tenderness around the eyes and cheekbones pounding in the ears shakiness in the legsarmshandsor feet shivering sweating swelling tenderswollen glands in the neck trembling or shaking of the hands or feet trouble sleeping trouble swallowing voice changes vomiting.
Combivent Inhalation Aerosol is a combination of the anticholinergic bronchodilatoripratropium bromideand the beta 2adrenergic bronchodilatoralbuterol sulfate.
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