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WarningContains trichloromonofluoromethaneCFC-11dichlorodifluoromethaneCFC-12and dichlorotetrafluoroethaneCFC-114substances which harm public health and the environment by destroying ozone in the upper atmosphere.

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In the 2 controlled 12-week studiesCOMBIVENT Inhalation Aerosol did not produce any change in the secondary efficacy parameters including symptom scoresphysician global assessments and morning PEFRall of which were monitored throughout the study period.

COMBIVENT Inhalation Aerosol has been used concomitantly with other drugsincluding sympathomimetic bronchodilatorsmethylxanthinesand oral and inhaled steroidscommonly used in the treatment of chronic obstructive pulmonary diseaseWith the exception of albuterolthere are no formal studies fully evaluating the interaction effects of COMBIVENT Inhalation Aerosol and these drugs with respect to safety and effectiveness.

Ipratropium bromide is an anticholinergicparasympatholyticagent whichbased on animal studiesappears to inhibit vagally-mediated reflexes by antagonizing the action of acetylcholinethe transmitter agent released at the neuromuscular junctions in the lungAnticholinergics prevent the increases in intracellular concentration of Cawhich is caused by interaction of acetylcholine with the muscarinic receptors on bronchial smooth muscle.

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if the outside of your combivent respimat inhaler gets dirty, wipe it with a damp cloth.

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