Digitalis administration of diltiazem with digoxin in 24 healthy male subjects increased plasma digoxin concentrations approximately 20 .

Information about Digoxin.
Do not stop taking digoxin without first talking to your doctorStopping suddenly may make your condition worse.
Not necessary to routinely reduce or hold digoxin therapy prior to elective electrical cardioversion for atrial fibrillationhoweverexclusion of digoxin toxicity is necessary prior to cardioverstionwhithhold digoxin and delay caridioversion until toxicity subsides if signs of digoxin excess exist.
Howeverit is important not to suddenly stop taking digoxin without having an alternative treatment planas there could be serious risk from the untreated heart problem.
The dosage of this medication is based on your medical conditionagebody weightlaboratory testsand response to treatment.
Digoxin comes as a tabletcapsuleor pediatric elixirliquidto take by mouthDigoxin is usually taken once a dayThe pediatric elixir comes with a specially marked dropper for measuring the doseIf you have difficultyask your pharmacist to show you how to use itIt is important that you always take the same brand of digoxinDifferent brands of digoxin have different amounts of active drug and your dose would need to be changed.
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alkylating agents moderate some antineoplastic agents have been reported to decrease the absorption of digoxin tablets due to their adverse effects on the gi mucosa; the effect on digoxin liquid is not known.