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Patients with uncontrolled hypertensioncongestive heart failureestablished ischaemic heart diseaseperipheral arterial diseaseand/or cerebrovascular disease should only be treated with piroxicam after careful considerationSimilar consideration should be made before initiating longer-term treatment of patients with risk factors for cardiovascular eventse.ghypertensionhyperlipidaemiadiabetes mellitussmoking
Tell your doctor right away if you have any serious side effectsincludingeasy bruising/bleedingdifficult/painful swallowinghearing changessuch as ringing in the earsmental/mood changessigns of kidney problemssuch as change in the amount of urineunexplained stiff neckvision changessymptoms of heart failuresuch as swelling ankles/feetunusual tirednessunusual/sudden weight gain
Because serious GI bleedinghepatotoxicityand renal injury can occur without warning symptoms or signsconsider monitoring patients on long-term NSAID treatment with a CBC and a chemistry profile periodicallysee Gastrointestinal BleedingUlcerationAnd PerforationHepatotoxicityRenal Toxicity And Hyperkalemia
Elevations of ALT or ASTthree or more times the upper limit of normalULNhave been reported in approximately 1of NSAID-treated patients in clinical trialsIn additionraresometimes fatalcases of severe hepatic injuryincluding fulminant hepatitisliver necrosisand hepatic failure have been reported.
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ankylosing spondylitis is a serious musculoskeletal disorder but contemporary medicine has gone that far that we have medications like feldene that help if not reverse time, then at least considerably slow down the degenerative processes in out bones.