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Men treated with cyclophosphamide may develop oligospermia or azoospermia associated with increased gonadotropin but normal testosterone secretionSexual potency and libido are unimpaired in these patientsBoys treated with cyclophosphamide during prepubescence develop secondary sexual characteristics normallybut may have oligospermia or azoospermia and increased gonadotropin secretionSome degree of testicular atrophy may occurCyclophosphamide-induced azoospermia is reversible in some patientsthough the reversibility may not occur for several years after cessation of therapyMen temporarily rendered sterile by cyclophosphamide have subsequently fathered normal children.
Interstitial pneumonitis has been reported as part of the postmarketing experienceInterstitial pulmonary fibrosis has been reported in patients receiving high doses of cyclophosphamide over a prolonged period.
Take this medication by mouth exactly as directed by your doctorThe dosage is based on your medical conditionweightresponse to treatmentand other treatmentssuch as other chemotherapy drugsradiationyou may be receivingBe sure to tell your doctor and pharmacist about all the products you useincluding prescription drugsnonprescription drugsand herbal products
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