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Should be used in caution in patients with moderate to severe hepatic impairment and/or severe impairment as the clearance of nicotine or its metabolites may be decreased with the potential for increased adverse effects.
Nicotinell patches should preferably be used in conjunction with a behavioural support programme.
Prepare to stop smoking by trying to reduce the number of cigarettes you smoke each day.
Program AIf you would like to stop smoking completely before starting the program:
Polycyclic aromatic hydrocarbons in tobacco smoke induce the metabolism of drugs catalysed by CYP 1A2and possibly by CYP 1A1When a smoker stopsthis may result in slower metabolism and a consequent rise in blood levels of such drugs.
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if you smoke less than 20 cigarettes a day start with nicotinell tts 20 14mg .