Cases of myopathy, including rhabdomyolysis, have been reported with simvastatin coadministered with colchicine, and caution should be exercised when prescribing vytorin with colchicine.
Information about Vytorin.
Frequency not reportedMyoglobinuriaacute renal failure secondary to rhabdomyolysisRef]
Check with your doctor immediately if any of the following side effects occur while taking ezetimibesimvastatin:
The combined use of VYTORIN with gemfibrozilcyclosporineor danazol is contraindicatedsee CONTRAINDICATIONS and DRUG INTERACTIONS
This medicine should not be given to a girl who has not yet had menstrual periods.
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the mean ldl-c in the study at one year was 53 mg dl in the vytorin arm and 70 mg dl in the simvastatin arm.