Coumadin patients are required to get their blood monitored frequently to make sure the dose of coumadin is safe.
Information about Coumadin.
Inhibitors of CYP2C91A2and/or 3A4 have the potential to increase the effectincrease INRof warfarin by increasing the exposure of warfarinInducers of CYP2C91A2and/or 3A4 have the potential to decrease the effectdecrease INRof warfarin by decreasing the exposure of warfarin.
If you’re planning to get pregnanttalk with your doctor about the problems you could have and what you can do to have a baby safely.
Stop using warfarin and call your doctor at once if you have a serious side effect such as:
Prothrombin complex concentratePCCfresh frozen plasmaor activated Factor VII treatment may be considered if the requirement to reverse the effects of COUMADIN is urgentA risk of hepatitis and other viral diseases is associated with the use of blood productsPCC and activated Factor VII are also associated with an increased risk of thrombosisThereforethese preparations should be used only in exceptional or life-threatening bleeding episodes secondary to COUMADIN overdosage.
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sulfamethoxazole trimethoprim can enhance the blood-thinning effects of warfarin coumadin , possibly leading to bleeding.