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Taking raloxifene increases the risk of blood clots in the lungs and legsbut does not appear to increase the risk of endometrial cancerIn postmenopausal women with osteoporosisdecreased bone densityraloxifene lowers the risk of breast cancer for women who have a high or low risk of breast cancerIt is not known if raloxifene would have the same effect in women who do not have osteoporosisTalk with your doctor about the risks and benefits of taking this drug.

In women with an increased risk of breast cancertaking aromatase inhibitors decreases the amount of estrogen made by the bodyBefore menopauseestrogen is made by the ovaries and other tissues in a woman’s bodyincluding the brainfat tissueand skinAfter menopausethe ovaries stop making estrogenbut the other tissues do notAromatase inhibitors block the action of an enzyme called aromatasewhich is used to make all of the body’s estrogenAromatase inactivators stop the enzyme from working.

In women with an increased risk of breast cancertaking aromatase inhibitors decreases the amount of estrogen made by the bodyBefore menopauseestrogen is made by the ovaries and other tissues in a woman’s bodyincluding the brainfat tissueand skinAfter menopausethe ovaries stop making estrogenbut the other tissues do notAromatase inhibitors block the action of an enzyme called aromatasewhich is used to make all of the body’s estrogenAromatase inactivators stop the enzyme from working.

Hormone therapy with estrogen only may be given to women who have had a hysterectomyIn these womenestrogen-only therapy after menopause may decrease the risk of breast cancerThere is an increased risk of stroke and heart and blood vessel disease in postmenopausal women who take estrogen after a hysterectomy.

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