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If you experience these effectsdo not drive or operate machinery until these effects have resolved.

The amount of levodopa absorbed by the body may be impaired if you eat a diet high in proteinAsk your doctorpharmacist or dietician to check your diet.

Carbidopa allows patients treated for Parkinson’s disease to use much lower doses of levodopaSome patients who responded poorly to levodopa have improved on SINEMETThis is most likely due to decreased peripheral decarboxylation of levodopa caused by administration of carbidopa rather than by a primary effect of carbidopa on the nervous systemCarbidopa has not been shown to enhance the intrinsic efficacy of levodopa.

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