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Clinical Experience in Type 2 Diabetes Mellitus Patients on Monotherapyor in Combination with SulfonylureasMetformin or InsulinPrecose was studied as monotherapy and as combination therapy to sulfonylureametforminor insulin treatmentThe treatment effects on HbA1c levels and one-hour postprandial glucose levels are summarized for four placebo-controlleddouble-blindrandomized studies conducted in the United States in Tables 2 and 3respectivelyThe placebo-subtracted treatment differenceswhich are summarized belowwere statistically significant for both variables in all of these studies.

Patients Receiving Sulfonylureas or InsulinSulfonylurea agents or insulin may cause hypoglycemiaPrecose given in combination with a sulfonylurea or insulin may cause a further lowering of blood glucose and may increase the potential for hypoglycemiaIf hypoglycemia occursappropriate adjustments in the dosage of these agents should be madeVery rarelyindividual cases of hypoglycemic shock have been reported in patients receiving Precose therapy in combination with sulfonylureas and/or insulin.

Ask your doctor how to adjust your acarbose dose if neededDo not change your medication dose or schedule without your doctor’s advice.

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