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Pfizer Australia has written to pharmacists providing further information about this issueincluding details of the process for this recall for product correction.

All patients should undergo a cardiovascular evaluationincluding echocardiogram to assess the potential presence of valvular diseaseIf valvular disease is detectedthe patient should not be treated with DOSTINEXSee CONTRAINDICATIONSPostmarketing cases of cardiac valvulopathy have been reported in patients receiving DOSTINEXThese cases have generally occurred during administration of high doses of DOSTINEX2mg/dayfor the treatment of Parkinson’s diseaseCases of cardiac valvulopathy have also been reported in patients receiving lower doses of DOSTINEX for the treatment of hyperprolactinemic disorders.

This medication is used to treat high levels of prolactin hormone in your bodyHigh levels of prolactin in women can cause symptoms such as unwanted breast milk and missed periods and can cause difficulty becoming pregnantHigh levels of prolactin in men can cause symptoms such as enlarged breasts and decreased sexual ability/desireCabergoline is an ergot medication and works by blocking the release of prolactin from the pituitary gland.

Fibrotic disorders can have an insidious onset and patients should be monitored for manifestations of progressive fibrosisThereforeduring treatmentattention should be paid to the signs and symptoms of:

DOSTINEX is not indicated for the inhibition or suppression of physiologic lactationUse of bromocriptineanother dopamine agonist for this purposehas been associated with cases of hypertensionstrokeand seizures.

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