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Indications the sterile preparation, terramycin with polymyxin b sulfate ophthalmic ointment, is indicated for the treatment of superficial ocular infections involving the conjunctiva and or cornea caused by terramycin with polymyxin b sulfate-susceptible organisms.

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In venereal diseases when coexistent syphilis is suspecteda dark field examination should be done before treatment is started and the blood serology repeated monthly for at least 4 months.

WARNINGSeriouslife threateninghypersensitivityanaphylacticreactions have been reported in some cats following application of antibiotic ophthalmic preparationsIf your cat has swelling of the faceitchingappears weakvomitsor has difficulty breathing within 4 hours of application you should discontinue treatment and contact your veterinarian immediately.

If renal impairment existseven usual oral or parenteral doses may lead to excessive systemic accumulation of the drug and possible liver toxicityUnder such conditionslower than usual total doses are indicated andif therapy is prolongedserum level determinations of the drug may be advisableThis hazard is of particular importance in the parenteral administration of tetracyclines to pregnant or postpartum patients with pyelonephritisWhen used under these circumstancesthe blood level should not exceed 15 mcg/ml and liver function tests should be made at frequent intervalsOther potentially hepatotoxic drugs should not be prescribed concomitantly.

Since bacteriostatic drugs may interfere with the bactericidal action of penicillinit is advisable to avoid giving tetracycline in conjunction with penicillin.

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