The effect of proton pump inhibitors ppi on the systemic exposure to the clopidogrel active metabolite following multiple doses of plavix 75 mg evaluated in dedicated drug interaction studies is presented in figure 1.
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Figure 2Cardiovascular DeathMyocardial Infarctionand Stroke in the CURE Study.
Certain other medicines may increase your risk of bleedingincluding aspirinAvoid taking aspirin unless your doctor tells you to.
75 mg PO qDay without a loading doserecommended as alternative to aspirin or concomitantly with aspirin if patient not at increased risk for bleeding but at high risk for cardiovascular disease.
Read the Medication Guide provided by your pharmacist before you start taking clopidogrel and each time you get a refillIf you have any questionsask your doctor or pharmacist.
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it is not known if plavix is safe and effective in children.