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You should not use this medication if you are allergic to granisetron, to similar medicines such as dolasetron anzemet , ondansetron zofran , or palonosetron aloxi .

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Keep the strip in the foil pouch until you are ready to use the medicineUsing dry handsremove the strip and place it on your tongueIt will begin to dissolve right awayDo not swallow the strip wholeAllow it to dissolve in your mouth without chewingSwallow several times after the strip dissolvesIf desiredyou may drink liquid to help swallow the dissolved stripWash your hands after using Zuplenz.

The use of ZOFRAN in patients following abdominal surgery or in patients with chemotherapy-induced nausea and vomiting may mask a progressive ileus and/or gastric distensionMonitor for decreased bowel activityparticularly in patients with risk factors for gastrointestinal obstruction.

Although some nonconjugated metabolites have pharmacologic activitythese are not found in plasma at concentrations likely to significantly contribute to the biological activity of ondansetron.

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