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VENTOLIN HFAlike all other beta2adrenergic agonistscan produce clinically significant cardiovascular effects in some patients such as changes in pulse rate or blood pressureIf such effects occurVENTOLIN HFA may need to be discontinuedIn additionbeta-agonists have been reported to produce electrocardiogramECGchangessuch as flattening of the T waveprolongation of the QTc intervaland ST segment depressionThe clinical relevance of these findings is unknownThereforeVENTOLIN HFAlike all other sympathomimetic aminesshould be used with caution in patients with underlying cardiovascular disordersespecially coronary insufficiencycardiac arrhythmiasand hypertension.
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Such a variation between clinical results and respondent feedback suggests that brand recognition alone may have been powerful enough to influence the preferences of the asthmatics who participated in the studyessentially producing a placebo effect.
The use of beta-adrenergic agonist bronchodilators alone may not be adequate to control asthma in many patientsEarly consideration should be given to adding anti-inflammatory agentse.gcorticosteroidsto the therapeutic regimen.
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